Coenzyme Q10 in sleep apnea studyMedical treatment with thiamine, coenzyme Q, vitamins E and C, and carnitine improved obstructive sleep apnea in an adult case of Leigh disease.
Combination therapy relevance noted
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
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